Aver CLI¶
Know whether your pipeline is still validated after every change.
The Aver CLI fingerprints a bioinformatics pipeline's dependencies, runs it on public Genome in a Bottle (GIAB) reference reads, and measures its SNV and indel performance with hap.py and the RTG vcfeval engine. It writes a deterministic, verifiable report you can file.
- Local and free. No account, and no network calls other than downloading reference data, the pipeline and its containers. No telemetry.
- Public reference materials only. Aver benchmarks against GIAB samples (HG001–HG007). It has no field anywhere for a patient identifier or a clinical sample, and it refuses any VCF whose sample is not a registered reference material.
- Reproducible. Reference data is verified against recorded SHA-256 checksums, containers are pinned by digest, and the same inputs always produce the same snapshot hash and byte-identical report.
Aver produces validation evidence. It does not certify, accredit or approve anything. Determinations about the fitness of a pipeline for clinical use remain the responsibility of the laboratory and its accrediting body.